منابع مشابه
The role of deoxycorticosterone in the biosynthesis of cardenolides in Digitalis lanata.
The role of deoxycorticosterone in the biosynthesis of digitoxigenin was investigated by the simultaneous administration of deoxy[1,2-(3)H(2)]corticosterone and [4-(14)C]progesterone to a Digitalis lanata plant. The biosynthetically formed [(3)H,(14)C]digitoxigenin and deoxy[(3)H,(14)C]corticosterone were isolated and the distribution of the two isotopes in these products was determined. The tr...
متن کاملDigitalis.
Cardiac glycosides have played a prominent role in the therapy of congestive heart failure since William Withering codified their use in his late 18th century monograph on the efficacy of the leaves of the common foxglove plant (Digitalis purpurea). Despite their widespread acceptance into medical practice in the ensuing 200 years, both the efficacy and the safety of this class of drugs continu...
متن کاملSynthetic cardenolides and related products.
ABSTRACT Since the publication in 1785 of one of the great classics of clinical medicine, 'An Account of the Foxglove and Some of its Medical Uses' by William Withering', the steroidal glycosides of digitalis have maintained a unique position among drugs. Their usefulness as life saving products is unchallenged and yet very few drugs are known to possess a narrower margin of safety. Their toxic...
متن کاملPharmacognostic evaluation of Bergenia ciliata (Haw.) Sternb
The present study was conducted to investigate the Bergenia ciliata (Haw.) Sternb. (Family: Saxifragaceae) for pharmacognostic study including macroscopical and microscopical observations, leaf surface features, Scanning Electron Microscopy and Fluorescence characters. The macroscopy revealed that rhizome was brown in color, hard in fracture, pleasant in odor and astringent in taste. Leaf was c...
متن کاملDigitalis Cardenolides by Plant Tissue Culture II. EFFECT OF LIGHT AND PLANT GROWTH SUBSTANCES ON DIGITOXIN FORMATION BY UNDIFFERENTIATED CELLS AND SHOOT-FORMING CULTURES OF DIGITALIS PURPUREA L. GROWN IN LIQUID MEDIA
Undifferentiated, highly chlorophyllous cell cultures; undifferentiated white cell cultures; green, shoot-forming cultures; and white, shoot-forming cultures of Digitalis parpurea L. were established and subcultured every 3 weeks in liquid media in the light or in the dark. The digitoxin content, the chlorophyll content, and the ribulose bisphosphate carboxylase activity of these cultures were ...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Chemistry of Natural Compounds
سال: 1973
ISSN: 0009-3130,1573-8388
DOI: 10.1007/bf00568659